克萊爾（德賽爾·霍爾 飾）與妹妹及兩個好友共赴拉斯維加斯，打算在結婚前再瘋狂一把。然而情況很快就超出了她們的預想……準新娘克萊爾，她的姐姐萊斯利，愛好樂趣佐伊，和古怪的新朋友珍妮動身去拉斯維加斯一一夜的單身派對，原來是超過他們的期望值。一系列意想不到的冒險，包括，被踢出一個脫衣舞俱樂部，被搶劫，被拉斯維加斯衛冕明膠摔跤冠軍，veronica，把他們從浮華和魅力的拉斯維加斯和將它們不偏不倚地在拉斯維加斯的破舊的軟肋。他們決定把單身派對的夢想，女孩捆綁在一起，踏上了瘋狂的夜晚在單身聚會的歷史。按性別和酒精，助長了這種不修邊幅，熱鬧熱鬧，失去控制，打擊的是，好的或壞的，都被錄。注定要跌過得最好的一個夜晚。

Bride-to-be Claire, her sister Leslie, fun-loving Zoe, and quirky new friend Janet set off to Las Vegas for a one-night bachelorette party that turns out to be more than they bargained for. A series of unexpected adventures including, getting kicked out of a strip club, being mugged and getting pummeled by the Las Vegas’ reigning gelatin-wrestling champion, Veronica, rip them from the glitz and glamour of the Las Vegas strip and places them smack dab in Vegas’ seedy underbelly. Determined to keep their bachelorette party dreams alive, the girls band together and embark on the wildest night in bachelorette party history. Fueled by sex and booze, this raunchy, riotously hilarious, out-of-control, blow-out is, for better or worse, all caught on tape. And is destined to go down as the Best Night Ever.